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.J. Forbes et al. Japan, year not Patients presenting to recruited all analysed offered hospitals with acute zoster, excluding individuals lately on immunosuppressive therapy, or with critical neurologic disorders; agedPHN at mo after zosterOpstelten et al.Netherlands, Individuals with zoster identified from EHRs from major care; any age identified all analysedNot availablePHN at mo immediately after zosterMedical code or zoster mentioned inside the totally free textconfirmed soon after evaluation of full health-related recordsPain at mo just after rash onset Any proof of pain in EHR; pain recordanalgesic prescriptionOpstelten Netherlands, Immunocompetent patients presenting to GPs with acute zoster and recruited into a trial; aged . y recruited all analysed not includedrefused consent, physician declined to participate, unknown.PHN at mo following zosterPhysician diagnosis inside d of rash onset, dermatome under CPain on VAS scale mo after study inclusion. Patient filled in postal surveyAge, gender, comorbid circumstances (diabetes, malignancy, immune disorders, autoimmune illness), prodromal pain, localization, severity of zoster rash, number of skin lesions, degree of acute pain, cerebrospinal fluid interleukin concentrations during and at healing of herpetic rash From previously recorded Age, gender, localization, healthcare records at zoster comorbidity (diabetes, diagnosis chronic obstructive pulmonary PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/17605643 disease, rheumatoid arthritis, systemic lupus erythematosus, psychological challenge at zoster diagnosis), medication at zoster diagnosis (corticosteroids within prior d and psychopharmaceuticals within earlier mo), painful prodrome, consultation frequency, chronic analgesics use Measured at Age, gender, rash baselinequestionnaire duration (in d) and and data from GP severity, prodromal pain, pain severity, use of antivirals, VZV antibodies (IgM, IgA, IgG), VZV viremia, and seven psychological predictorsnegative selfefficacy, discomfort catastrophizing, good expectation, resignation, and trust in well being care, anxiety state and anxiousness dispositionLogistic regressionLogistic regression Logistic regression Pain(continued on subsequent web page)Copyright by the International Association for the Study of Pain. Unauthorized reproduction of this short article is prohibited.Table (continued)Cohort studies Initially author publication year Country, year Study population of study Study size Imply (SD) Outcome age in years at baseline Patients with Definition and PHN, n technique of identifying zoster Definition and method of ascertaining PHN Approach of ascertaining danger issue(s) Risk components assessed Statistical analysisJanuaryVolumePark et al. South Korea, JNJ16259685 web sufferers presenting to hospital with acute zoster; any age recruited all analysedPHN patientsPHN at mo immediately after . zoster NonPHN.Physician Pain persisting or Collected at diagnosis within appearing baselinemethod d of rash onset d immediately after rash onset unclear System unclearParruti et al.Italy,Consecutive sufferers presenting to primary care or hospital with acute zoster; age unspecified recruited . analysed lost to followupPHN mo after zosterPhysician diagnosis any time soon after rash onset, with laboratory investigation of uncertain casesAny discomfort in between Patient completed mo immediately after electronic forms at Bretylium (tosylate) enrolment enrolment Recorded at followup stop by or by telephoneVolpi et al. Italy,Sufferers with immunocompetent zoster presenting to private dermatologists, aged y recruited analysedMedian agePHN mo right after zoster Doctor diagnosisPain mo soon after rash onset, with discomfort rating or hig..J. Forbes et al. Japan, year not Patients presenting to recruited all analysed offered hospitals with acute zoster, excluding sufferers lately on immunosuppressive therapy, or with significant neurologic problems; agedPHN at mo immediately after zosterOpstelten et al.Netherlands, Sufferers with zoster identified from EHRs from primary care; any age identified all analysedNot availablePHN at mo soon after zosterMedical code or zoster mentioned inside the no cost textconfirmed after evaluation of complete medical recordsPain at mo just after rash onset Any evidence of pain in EHR; pain recordanalgesic prescriptionOpstelten Netherlands, Immunocompetent sufferers presenting to GPs with acute zoster and recruited into a trial; aged . y recruited all analysed not includedrefused consent, doctor declined to participate, unknown.PHN at mo soon after zosterPhysician diagnosis within d of rash onset, dermatome below CPain on VAS scale mo following study inclusion. Patient filled in postal surveyAge, gender, comorbid conditions (diabetes, malignancy, immune issues, autoimmune illness), prodromal discomfort, localization, severity of zoster rash, variety of skin lesions, degree of acute discomfort, cerebrospinal fluid interleukin concentrations throughout and at healing of herpetic rash From previously recorded Age, gender, localization, healthcare records at zoster comorbidity (diabetes, diagnosis chronic obstructive pulmonary PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/17605643 illness, rheumatoid arthritis, systemic lupus erythematosus, psychological issue at zoster diagnosis), medication at zoster diagnosis (corticosteroids within prior d and psychopharmaceuticals inside preceding mo), painful prodrome, consultation frequency, chronic analgesics use Measured at Age, gender, rash baselinequestionnaire duration (in d) and and information from GP severity, prodromal discomfort, pain severity, use of antivirals, VZV antibodies (IgM, IgA, IgG), VZV viremia, and seven psychological predictorsnegative selfefficacy, discomfort catastrophizing, good expectation, resignation, and trust in health care, anxiousness state and anxiousness dispositionLogistic regressionLogistic regression Logistic regression Pain(continued on subsequent web page)Copyright by the International Association for the Study of Pain. Unauthorized reproduction of this short article is prohibited.Table (continued)Cohort research Initially author publication year Country, year Study population of study Study size Mean (SD) Outcome age in years at baseline Sufferers with Definition and PHN, n method of identifying zoster Definition and technique of ascertaining PHN Process of ascertaining risk issue(s) Risk variables assessed Statistical analysisJanuaryVolumePark et al. South Korea, Patients presenting to hospital with acute zoster; any age recruited all analysedPHN patientsPHN at mo soon after . zoster NonPHN.Doctor Discomfort persisting or Collected at diagnosis within appearing baselinemethod d of rash onset d immediately after rash onset unclear Technique unclearParruti et al.Italy,Consecutive sufferers presenting to primary care or hospital with acute zoster; age unspecified recruited . analysed lost to followupPHN mo following zosterPhysician diagnosis any time after rash onset, with laboratory investigation of uncertain casesAny pain amongst Patient completed mo just after electronic forms at enrolment enrolment Recorded at followup go to or by telephoneVolpi et al. Italy,Individuals with immunocompetent zoster presenting to private dermatologists, aged y recruited analysedMedian agePHN mo immediately after zoster Doctor diagnosisPain mo following rash onset, with pain rating or hig.

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