Product Name :
Rabbit anti-SFRP5 Polyclonal Antibody(Center)
Synonym :
Secreted frizzled-related protein 5; sFRP-5; Frizzled-related protein 1b; FRP-1b; Secreted apoptosis-related protein 3; SARP-3; SFRP5; FRP1B; SARP3
Host :
Rabbit
Species Reactivity:
Human, Mouse
Specificity :
This SFRP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-219 amino acids from the Central region of human SFRP5.
Predicted Reactivity:
Bovine
Applications :
WB~~1:1000IHC-P~~1:10~50
Immunogen:
Concentration :
Purification :
Clonality:
Polyclonal Antibody
Storage Temp.:
Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles
Research areas :
Stem Cells;Others
Background :
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina.
UniProt :
Q5T4F7
Additional information:
Product Details FAQ Citations(0) Video Pictures Documents |Overview |Synonym Secreted frizzled-related protein 5; sFRP-5; Frizzled-related protein 1b; FRP-1b; Secreted apoptosis-related protein 3; SARP-3; SFRP5; FRP1B; SARP3 |Host Rabbit |Specificity This SFRP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-219 amino acids from the Central region of human SFRP5. |Species Reactivity Human, Mouse |Predicted Reactivity Bovine |Applications WB~~1:1000IHC-P~~1:10~50 |Properties |Clonality Polyclonal Antibody |Isotype Rabbit Ig |Storage Temp. Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles |Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |Research areas Stem Cells;Others |Target |Background Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina. |Cellular localization Secreted. |UniProt Q5T4F7 |References |References Su, H.Y., et al. Int. J. Cancer 127(3):555-567(2010)Sharma, S., et al. Am. J. Respir. Crit. Care Med. 181(4):328-336(2010)Jost, E., et al. Cancer Lett. 281(1):24-31(2009)Zhao, C., et al. BMC Cancer 9, 224 (2009) :Tanaka, J., et al. Hepatogastroenterology 55(85):1265-1268(2008) |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-SFRP5 Polyclonal Antibody(Center)
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
2739844-34-7 supplier 920509-32-6 custom synthesis PMID:20301690 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com
